Elanco Animal Health

www.elanco.com

Product : Veterinary Medicine

20 Anti-coccidial- Clinacox 0.5% Premix (Diclazuril 0.5%)Active ingredient: Each kg contains 5 grams of diclazuril FOR FEED MANUFACTURING USE ONLY. Indications: As an aid in the prevention of coccidiosis caused by Eimeria acervulina, E. brunetti, E. maxima, E. mitis, E. necatrix and E. tenella in broiler chickens. As an aid in the prevention of coccidiosis caused by Eimeria adenoeides, E. meleagrimitis and E. gallopavonis in growing turkeys. Dosage and Administration: Broiler Chickens: Use 0.0001% diclazuril medicated feed as the sole ration (500gm per ton of feed) from day 1 to slaughter. Growing Turkeys: Use 0.0001% diclazuril medicated feed as the sole ration (500gm per ton of feed) from day 1 to a maximum of 14 weeks of age. Caution: 1. Do not use diclazuril medicated feed for the treatment of outbreaks of coccidiosis. 2. If unexpected deaths occur, obtain an accurate diagnosis and follow Veterinarian’s or poultry pathologist’s recommendations. 3. Do not use with pellet binding agents except Pel-Aid or Lignin Sulfonate. Treatment applies for: Chicken and Turkey. Storage: Store under dry conditions. Pack Size: 20 kg bag. Origin: European origin. Manufactured and distributed by: Elanco, Division of Eli Lilly Inc., USA
21 Clinafarm Spray 150 mg/ml

Active substances: Enilconazole 150 mg/ml or 15% per liter. Benzyl alclhol 100 mg as emulsifying agent as preservative. Dioctyl sodium sulfosaccinate 75% (m/m) solution 450 mg and Macrogol 40 castor oil-q.s ad 1,000µl as emulsifying agent.  Presentation : 1000 ml bottle of emulsifiable concentration. Uses: Environmental disinfection and prevention of infestation by fungi/fungus. Dosage and Administration: Before use, clean the surfaces that will be disinfected.

Clinafarm should always be used diluted in water at a ratio of 1 to 100 (10 ml/litre of water) to form an emulsion containing 1.5 mg of active substance/litre. Remove or cover all the feeding and drinking troughs during spray by Clinafarm. Pack size: 1000 ml/1 litre, 100 ml amber glass bottle. Storage : Store at room temperature. Danger : Keep out of reach of children.  Avoid breathing spray mist and contact with skin. Don’t use or store near heat or open flame. Do not contaminate with water, food or feed by storage. Harmful if absorbed through skin or inhaled.  Precautions: Hazards to Human and domestic animals. Origin : Eli Lilly and Company Limited, Fleming Road, Speke, Liverpool L24 9 LN.UK. Under manufacturer company Lusomedicamenta-Sociedade Tecnica Farmaceutica, S.A, Estrade Consiglieri Pedroso, n.69/B, Queluz De Baixo, 2730055 Baracarena, Portugal.

22 Elancoban® 200

(A Ionophore anti-coccidial)

Composition: (Monensin Sodium 200 gms / kg), Indication: A protozoal disease of intestine caused by Eimeria spp in chicken. There are 11 different species isolated from various avian types, of which 6 species are considered to be very pathogenic in chickens. Epidemiologically, E. acervulina, E. maxima and E. tenella are most commonly seen under commercial operation in poultry. A proven product that controls coccidiosis, improves feed conversion and delivers dried litter resulting in better bird health and a greater economic performance. Its proven year round exclusive choice for high challenge conditions, controls better multiple species of coccidia and secondary pathogens, effective against gm+ bacteria organisms, better litter quality especially in rainy and winter season and effective cocci control in replacement pullets(layers and breeders).

Caution : Do not allow horses or other equines acciss to formulation containing Maxiban®, Monteban® and Elancoban®. Pleuromulins, like tiamulin should not be feed simultaneously to the bird either through feed or water when Maxiban, Monteban and Elancoban is being used. Dosage : 500-600 gm/ton (100-120 ppm of monensin / ton of broiler, layer and breeder feed), Pack Size : 25 kg bag, Elanco Animal Health U.S.A, Origin : U.S.A. / U. K

23 Product Name : Hemicell®-HT

Hemicell®-HT is a heat tolerant feed enzyme system developed to improve the nutritional value of poultry and swine diets based on soy and other ingredients with ß-mannan fiber content. Like the Hemicell®-HT product, Hemicell®-HT adds value to manufacturers by improving animal live performance, as measured by better feed efficiency, greater uniformity of live-weights, and higher livability. This new product is more thermally stable and may be applied to the feed mixer pre-pelleting without heat-inactivation of the enzyme. Hemicell®-HT has been shown to retain more than 80% activity under conditioning and pelleting temperatures up to 88° C.

Guaranteed Enzyme Activity : ß-Mannanase (EC 3.2.1.78) from Bacillus lentus: 72.5 million units/lb, minimum for Hemicell®-HT (powder form); and 590 million units/liter, minimum for Hemicell®-HT Liquid (liquid form).

Recommended Application Rate Mix 0.45-0.80 lb of Hemicell®-HT per ton of feed directly into the feed mixer before pelleting. Alternatively, if a liquid additive is preferred, dilute Hemicell®-HT Liquid with potable water and spray into the mixer at the rate of one liter per ton of feed. The enzyme product should be mixed with water using an in-line dilution system such that 50 ml product are mixed with 950 ml water (or 100 ml product are mixed with 900 ml water). Like the powder form, Hemicell®-HT Liquid is intended to be added to the mixer prior to pelleting.

Product Appearance and Quality, Hemicell®-HT is a light brown powder and Hemicell®-HT Liquid is a light brown liquid product. Hemicell®-HT and Hemicell®-HT Liquid meet or exceed the regulatory requirements of the jurisdictions where they are sold. No animal origin ingredients are used in production. Product Packaging, Hemicell®-HT is sold in 25-kg multiwall paper bags with a polyethylene liner. Hemicell®-HT Liquid is supplied in 208 L (55-gallon) plastic drums and in 1249 L (330-gallon) re-useable totes. Safe Handling Feed enzyme products may cause dermal and respiratory irritation and/or sensitivity. Appropriate protective clothing and equipment should be used during handling. Consult the product safety sheet for further information.

Recommended Storage, Store product in closed containers at 75° F or below. These products will meet the guaranteed level of enzyme activity for 12 months provided that they have been stored according to this recommendation. Hemicell®-HT is the registered trademark of ChemGen Corp. Hemicell®-HT may be used under RE 38047, and US 6,162,473, and Patent Pending.

The information contained herein is correct to the best of our knowledge. The recommendations or suggestions contained in this data sheet are made without guarantee or representation as to results. We suggest that you evaluate these recommendations and suggestions in your own laboratory prior to use. Our responsibility for claims arising from breach of warranty, negligence, or otherwise is limited to the purchase price of the material. Freedom to use any patent owned by ChemGen or others is not to be inferred from any statement contained herein. General Dosage : 220 – 400 gm / ton of feed. Pack Size : 25 kg Bag. Using Species : Broilers, Layers, Breeders, Fish etc. Eli Lilly and Co. USA. Web : elanco.com

24 Monteban® 45

(A Ionophore anti-coccidial)Composition: Narasin 100 gms / kg, Indications : Monteban® use only for broiler feed, its provides cocci / enterits control, bird eating even in warm weather and maintains pigmentation, good health, improves performance, ROI and protects intestinal integrity for broiler. Description : A protozoal disease of intestine caused by Eimeria spp in chicken. There are 11 different species isolated from various avian types, of which 6 species are considered to be very pathogenic in chickens. Epidemiologically, E. acervulina, E. maxima and E. tenella are most commonly seen under commercial operation in poultry. A proven product that controls coccidiosis, improves feed conversion and delivers dried litter resulting in better bird health and a greater economic performance. Its proven year round exclusive choice for high challenge conditions, controls better multiple species of coccidia and secondary pathogens, effective against gm+ bacteria organisms, better litter quality especially in rainy and winter season and effective cocci control in replacement pullets(layers and breeders). Caution : Do not allow horses or other equines access to formulation containing Maxiban®, Monteban® and Elancoban®. Pleuromulins, like tiamulin should not be feed simultaneously to the bird either through feed or water when Maxiban®, Monteban® and Elancoban® is being used. Dosage : 600-800 gm/ton of broiler feed (60-80 ppm of narasin / ton of broiler feed) Pack Size : 25 kg bag, Elanco Animal Health, Origin : U.S.A./U.K

25 Maxiban®

(Composition: Combination of Narasin and Nicarbazin (Narasin 80 gm / kg + Nicarbazin 80 gm/kg). Indications : Narasin use only for broiler feed, Maxiban® a synergistic essential product uniquely optimizing control of coccidiosis and enteritis to achieve bird health and performance, Superior Intestinal Integrity, Maximum performance and year round starter / grower option. Why Maxiban® : Long term efficacy, better FCR / ROI / gain, better MIC levels against C. perfingence, better control than straight ionophores, efficacious against all Eimeria spp. and allows immunity to develop, Description : A protozoal disease of intestine caused by Eimeria spp in chicken. There are 11 different species isolated from various avian types, of which 6 species are considered to be very pathogenic in chickens. Epidemiologically, E. Acervulina, E. maxima and E. tenella are most commonly seen under commercial operation in poultry. A proven product that controls coccidiosis, improves feed conversion and delivers dried litter resulting in better bird health and a greater economic performance. Its proven year round exclusive choice for high challenge conditions, controls better multiple species of coccidia and secondary pathogens, effective against gm+ bacteria organisms, better litter quality especially in rainy and winter season and effective cocci control in replacement pullets(layers and breeders). Caution : Do not allow horses or other equines access to formulation containing Maxiban®, Monteban® and Elancoban®. Pleuromulins, like tiamulin should not be feed simultaneously to the bird either through feed or water when Maxiban®, Monteban® and Elancoban® is being used. Usage : In broiler per-starter and starter feed as per recommended dose from day 1 to 28th day. Dosage : Maxiban : 375-560 gm/ton of broiler feed (60-90 ppm of narasin & nicarbazin / ton of pre-starter and grower broiler feed), Pack Size : 25 kg bag, Elanco Animal Health, USA. Origin : USA

26 Pulmotil® AC

Description : Improve Immunity, Better Vaccine Response, Reduce Vaccine Reaction. Pulmotil® AC is a new, highly effective liquid formulation of tilmicosin, a macrolide antibiotic that makes it better choice for control and treatment of respiratory disease in chickens, thus improving health and overall performance. Besides, several other benefits, use of Pulmotil® AC can result in improved immunity, better vaccine response and reduction in abnormal vaccine reactions.  Efficacy : Pulmotil® AC is quickly absorbed and concentrates in respiratory tissues, and accumulates in phgocytes (macrophages, heterophils). Tilmicosin pulmonary and air sac concentrations persist at significant levels for at least 48 hours following application. This long payout provides extended protection and value for growers. Stability : Pulmotil® AC is formulated to offer the highest possible, long-term stability. To ensure a long shelf life, Pulmotil® AC comes in special polymer bottles that protect against moisture loss, oxygen and light. Once the bottle is open Pulmotil® AC remains stable for at least three months. In final drinking water, Pulmotil® AC is stable for up to four days. (Elanco recommends changing final drinking water mixture every 24 hours). Composition: (Tilmicosin 250 mg / ml), Mode of Action : Pulmotil® AC has a unique mode of action. Because of its high distribution volume, it moves quickly throughout the bird’s body, including the respiratory tissues. Works along with the defence mechanism of the Bird & synergistically ensures a better immune response by the Bird. This way the Bird is able to effectively fight disease causing pathogens. Within six hours of medication, Pulmotil® AC achieves levels above the MICs of target pathogens in lung and air sac tissues. These levels persist well beyond the treatment period. This extended payout increases the efficacy period of Pulmotil® AC. Dosage : 20 mg Tilmicosin/kg body weight or 0.08 ml Pulmotil AC/ kg body weight. For 3-5 days with any other gram negative antibiotics. Pack Size : 240 ml bottle, Elanco Animal Health, U.S.A., Origin : UK

27 Tylan® Soluble(Oral administration against Mycoplasma (CRD) infection in poultry )Composition : Tylosin tartrate eqivalent to 100 gm tylosin base or Pure or 100%. Indications : Tylan® is trade mark for ELANCO’s brand of tylosin tartrate. Tylan® Soluble provides high activity against Mycoplasma gallisepticum and Mycoplasma synoviae. Tylan® Soluble works as a preventive and as a treatment against Mycoplasmosis. Dosage : 110 mg / kg body weight, Pack Size : 100 gm cont, Elanco Animal Health, U.S.A., Origin : U.K.